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repeated dietary exposure

process / process-repeated-exposure

反復曝露

Repeated dietary exposure is a regimen used in simple-exposure interventions in which a food is tasted repeatedly without an accompanying reward.

On this page (6 sections)
  1. Overview
  2. Sources for this overview (4)
  3. Topic hubs
  4. Follow the connections
  5. Related entries (5)
  6. Sensory (5)
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Reading the bitterness

Repeated exposure is an intervention that has people taste the same food repeatedly without a reward, aiming to change liking or intake of that food. Bitterness is cited as one major reason children reject vegetables, and becoming accustomed to vegetables, including bitter ones, underlies this analysis. A meta-analysis mainly of infants and young children, covering 43 papers and 117 comparisons, found higher vegetable liking (standardized mean difference 0.35) and intake (0.23) with repeated exposure than with no exposure. This corresponded to about 0.6 points on a 9-point liking scale. However, the authors themselves say 「効果量は小さい」 (in translation: "the effect sizes are small"); many included studies had high risk of bias, and comparisons were not stratified by bitterness intensity.

In the same analysis, the effect on liking for a novel vegetable did not persist to the longest follow-up (standardized mean difference 0.15, not statistically significant). In contrast, a study of 95 infants who had just begun complementary feeding reported that improved liking after 10 repeated exposures to artichoke purée remained stable for three months after exposure. Because the age groups differ, this may indicate age-related differences in how long an effect persists rather than a contradiction.

In one adult study, after a commercially available bitter-sweet drink was consumed at home once daily for 7 days, liking for that drink rose 68%, while a control drink tasted only in the laboratory did not change. In another experiment, repeated consumption for two weeks of EGCG, a tea catechin dissolved in water, reduced ratings of bitterness for that same EGCG solution compared with repeated consumption of water alone. These results concern a particular compound and a particular drink; they cannot be generalized to dishes or foods as a whole.

Sources for this overview

  1. Repeated exposure and conditioning strategies for increasing vegetable liking and intake: systematic review and meta-analyses

    Appleton KM; Hemingway A; Rajska J; Hartwell H / 2018 / review / full text checked

    Checked for this overview: Checked effect sizes for liking and intake after repeated exposure. / Checked the authors' summary that effect sizes were small. / Checked that the effect did not persist to the longest follow-up.

  2. Repeated exposure of infants at complementary feeding to a vegetable puree increases acceptance as effectively as flavor-flavor learning and more effectively than flavor-nutrient learning

    Remy E; Issanchou S; Chabanet C; Nicklaus S / 2013 / journal article / abstract checked

    Checked for this overview: Checked that the infant effect remained stable through 3 months.

  3. Effects of repeated exposure and health-related information on hedonic evaluation and acceptance of a bitter beverage

    Stein LJ; Nagai H; Nakagawa M; Beauchamp GK / 2003 / journal article / abstract checked

    Checked for this overview: Checked a 68% increase in liking after 7 days of exposure to the bitter-sweet drink.

  4. Repeated exposure to epigallocatechin gallate solution or water alters bitterness intensity and salivary protein profile

    Davis LA; Running CA / 2021 / journal article / full text checked

    Checked for this overview: Checked lower bitterness ratings after 2 weeks of repeated EGCG consumption.

Follow the connections

repeated dietary exposure →can decrease→ bitterness →can be measured separately …→ astringency

Structured claims — open a section to read each claim's confidence, evidence and limits

Sensory (5)

repeated dietary exposure increases Liking of vegetables (SMD 0.35 [0.17, 0.53]) and intake (SMD 0.23 [0.07, 0.39]), compared with no exposure. About 0.6 points on a 9-point liking scalesupported

Scope: A meta-analysis of between-subjects comparisons (the review as a whole covered 43 papers and 117 comparisons; this result rests on 17 comparisons and 820 participants for liking, and 21 comparisons and 1130 participants for intake). Mainly infants and children

Note: The effect size is small, and many of the original studies are at high risk of bias. Bitterness is mentioned as a major factor in vegetable rejection, but there is no analysis stratified by bitterness intensity.

Repeated exposure raised post-intervention liking compared with no exposure (SMD 0.35 [0.17, 0.53]; 17 comparisons, 820 participants), and also raised intake (SMD 0.23 [0.07, 0.39]; 21 comparisons, 1130 participants). This corresponds to about 0.6 points of liking on a 9-point scale, and about 10 g of vegetable.
Limitations: Most of the included studies are small and at high risk of bias. Heterogeneity is low (I2 25-29%), but the effect size is small.
Source: Repeated exposure and conditioning strategies for increasing vegetable liking and intake: systematic review and meta-analyses (Appleton KM; Hemingway A; Rajska J; Hartwell H, 2018) · full text checked
Limits: The authors state that effect sizes are small and that evidence for long-term benefits is limited. Follow-up after the intervention was often limited.
Limitations: Follow-up periods were inconsistent; the authors themselves acknowledge limitations in adherence and reporting.
Source: Repeated exposure and conditioning strategies for increasing vegetable liking and intake: systematic review and meta-analyses (Appleton KM; Hemingway A; Rajska J; Hartwell H, 2018) · full text checked
8 daily tasting sessions of sweet red pepper significantly increased liking (P = 0.006) and intake (P = 0.03) compared with a no-treatment control. The sticker-reward condition was intermediate, not differing significantly from either group.
Limitations: A single vegetable (sweet red pepper, not strongly bitter). Small sample. Abstract-level reading only.
Source: Modifying children's food preferences: the effects of exposure and reward on acceptance of an unfamiliar vegetable (Wardle J; Herrera ML; Cooke L; Gibson EL, 2003) · abstract checked
Show dataprocess-repeated-exposure —increases→ (the claim sentence above)
claim: clm-repeated-exposure-increases-vegetable-liking / type: sensory / updated: 2026-10-21
repeated dietary exposure has limited long-term persistence of Improvement in liking: for a novel vegetable that had not itself been exposed, no significant effect was detected at the longest follow-up (0-6 years after the intervention) (SMD 0.15 [-0.21, 0.50], P = 0.41; 12 comparisons, 535 participants). Liking for the same vegetable that had been exposed was maintained at about 1.5 months of follow-up (SMD 0.30)supported

Scope: A follow-up analysis within the same meta-analysis (between-subjects comparisons). Follow-up periods were often short and inconsistent

Note: The authors' overview: 『Effect sizes, however, are small, and limited evidence suggests long-term benefits』. A counter/limiting claim showing the limits of the durability of acquired liking. Durability may be age-window dependent: in infants (95 in all, 32 in the basic-purée group), learning to accept the same vegetable was stable up to 3 months later (Remy 2013). That result concerns the same repeated vegetable, a different question from durability of liking for a different new vegetable, so on 2026-10-21 the evidence relation was changed from contradicts to contextualizes (in checking the question on whether people stop disliking bitter vegetables with repetition).

For liking of a novel vegetable that had not itself been exposed, no significant effect was detected at the longest follow-up (0-6 years after the intervention) (SMD 0.15 [-0.21, 0.50], P = 0.41; 12 comparisons, 535 participants). There was an effect just after the intervention (SMD 0.38). The authors state that when measured at follow-up, effects had generally decreased. Liking for the same vegetable that had been exposed was maintained at about 1.5 months of follow-up (SMD 0.30).
Limitations: Few studies measured long-term outcomes, and the range of follow-up periods is wide (up to several years at most).
Source: Repeated exposure and conditioning strategies for increasing vegetable liking and intake: systematic review and meta-analyses (Appleton KM; Hemingway A; Rajska J; Hartwell H, 2018) · full text checked
Context: In a trial that split 95 French infants at the start of complementary feeding (6.4 +/- 0.8 months) into 3 groups, the group exposed 10 times to a basic artichoke purée (RE group, 32 infants) increased intake by +63% and liking by +21% (the sweetened-purée group increased intake by +39% with no increase in liking, and the energy-dense-purée group showed no significant increase in either). The abstract says that learning to accept artichoke was stable up to 3 months after exposure (the abstract does not state which group this refers to). This concerns continued acceptance of the same repeated vegetable, a different question from the meta-analysis finding at the longest follow-up (liking for a different new vegetable after offering a variety), so it is not a conflicting result.
Limitations: The stability described explicitly in the abstract covers up to 3 months. A 6-month follow-up was part of the design, but its result is not reported in the abstract, so persistence beyond 3 months is untested here. The liking scale and the names of the statistical tests are not in the abstract. Whether this trial is included in the meta-analysis, and how its age range differs from the meta-analysis population, cannot be confirmed from this abstract.
Show dataprocess-repeated-exposure —has_limited_long_term_persistence_of→ (the claim sentence above)
claim: clm-exposure-effect-durability-limited / type: sensory / updated: 2026-10-22
repeated dietary exposure increases Participants' hedonic ratings of a bittersweet beverage (+68% after drinking it 1 time a day for 7 days in a setting of their choosing). Meanwhile, control stimuli tasted only in the laboratory did not changesupported

Scope: Participants (number and age not given in the abstract), 1 commercially available bittersweet beverage (Stein 2003)

Note: A single study. The beverage's composition (presence or absence of caffeine) and n are not reported in the abstract, and the mechanistic attribution (post-ingestive association) remains the authors' speculation.

After consuming a commercially available bittersweet beverage 1 time a day for 7 days in a setting of the participants' choosing, hedonic ratings of that beverage rose by 68%, while ratings of control stimuli tasted only in the laboratory did not change; health-related information did not affect the perceptual changes that accompanied exposure.
Limitations: The abstract shows neither the beverage's composition (caffeine content) nor the sample size; a single study; the mechanistic attribution is the authors' speculation.
Source: Effects of repeated exposure and health-related information on hedonic evaluation and acceptance of a bitter beverage (Stein LJ; Nagai H; Nakagawa M; Beauchamp GK, 2003) · abstract checked
Context: In 20 moderate caffeine consumers, pleasantness ratings of a novel-flavoured drink paired with caffeine (CS+) rose gradually over 8 breakfast conditioning trials, while the drink paired with placebo (CS-) did not change. The authors conclude that the change is best explained by Pavlovian associations between drink flavour and the post-ingestive effects of caffeine, giving direct experimental support to the post-ingestive mechanism that Stein 2003 could only infer.
Limitations: Since the abstract does not describe this beverage as bitter, this does not reproduce the result for bittersweet beverages, but rather contextualizes the acquisition mechanism for caffeinated beverages in general. Despite the change in pleasantness, overall preference did not change.
Source: Flavour liking and preference conditioned by caffeine in humans (Yeomans MR; Durlach PJ; Tinley EM, 2005) · abstract checked
Context: Health-related information did not affect the perceptual (hedonic) change accompanying exposure itself, but tended to somewhat increase the behavioral measure of acceptability. The authors interpret this as information potentially acting more strongly on behavior than on hedonic evaluation.
Limitations: Stops at a 『傾向』 (in translation: "tendency"), and the abstract does not report statistical significance. The definition and measurement method of the behavioral measure (acceptability) are also absent from the abstract. Full text not reached (Elsevier/Appetite, Unpaywall closed, no repository copy).
Source: Effects of repeated exposure and health-related information on hedonic evaluation and acceptance of a bitter beverage (Stein LJ; Nagai H; Nakagawa M; Beauchamp GK, 2003) · abstract checked
Show dataprocess-repeated-exposure —increases→ (the claim sentence above)
claim: clm-adult-bitter-beverage-exposure-liking / type: sensory / updated: 2026-10-22
repeated dietary exposure can decrease bitternesssupported

Scope: An evaluation after repeatedly taking EGCG, a type of tea catechin, dissolved in water for 2 weeks

Note: This is a comparison with repeating water alone, and does not show a mechanism of becoming accustomed to all foods.

After repeatedly taking EGCG dissolved in water for 2 weeks, the bitterness rating for the same EGCG solution was lower than after repeating water alone.
Limitations: This is a result from examining a single compound dissolved in water over a short period, and cannot be extended to cooking or food in general.
Show dataprocess-repeated-exposure —can_decrease→ sensation-bitter
claim: clm-egcg-repeated-exposure-bitterness / type: sensory / updated: 2026-08-31
repeated dietary exposure does not significantly influence A test conducted after 14 days to distinguish saltiness, sweetness, sourness, and bitterness, and an intensity evaluationpreliminary

Scope: A small pilot study of 10 healthy women using an oral gel containing capsaicin

Note: This is a result in which no difference was found in a trial with few participants, and is not proof that there is no effect at all.

Before and after using the capsaicin-containing gel in the mouth for 14 days, there was no statistically clear change in the performance of distinguishing saltiness, sweetness, sourness, and bitterness, or in the perceived intensity.
Limitations: This is a small pilot study, and there are also limitations in how the comparison group was set up. It is not proof that there is no effect at all.
Source: Effects of Oral Topical Capsaicin Gel on Taste Perception in Healthy Subjects: A Pilot Study (Rupel K; Buoite Stella A; Tamos M; Adamo D; Canfora F; Biasotto M; Di Lenarda R; Ottaviani G, 2025) · full text checked
Show dataprocess-repeated-exposure —does_not_significantly_influence→ (the claim sentence above)
claim: clm-capsaicin-basic-taste-null-pilot / type: sensory / updated: 2026-08-31

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