日本語版

Andean lupin

organism / organism-lupinus-mutabilis

アンデスルピナス / Lupinus mutabilis

Andean lupin is a legume crop native to the Andes. Its seeds are high in protein but contain bitter quinolizidine alkaloids; they are traditionally debittered with water before eating.

Photographs (captions in Japanese)

Butterfly-shaped flowers mixed blue-violet and white, in clusters at the tips of several stems standing in a field. The leaves are palmate compound leaves shaped like spread fingers.

Cultivated plants of Andean lupin (Lupinus mutabilis, tarwi). In a field near Puno, Peru, flower spikes with blue-violet and white flowers and palmate compound leaves are shown.

Shown: Lupinus mutabilisPart / state: Cultivated plants in the flowering period (blue-violet and white flower spikes, palmate compound leaves)

Photo: Michael Hermann / CC BY-SA 4.0 / original image / ledger's original image

Scope and provenance of the photo

Identification: Identified as labelled in the source. The source describes it as a cultivated plant (grown for its edible seeds) near Puno, Peru, at an altitude of about 3800 m. Re-identification by a specialist has not been done.

Image shown: The 1920 px version from Wikimedia Commons. No cropping or color changes by NIGAMI LAB. For display, a WebP capped at 1200 px wide is served; the ledger's original image can be checked from the link above.

On this page (7 sections)
  1. Overview
  2. Sources for this overview (2)
  3. Topic hubs
  4. Follow the connections
  5. Related entries (5)
  6. Measured values (1)
  7. Composition and content (3)
↑

Reading the bitterness

Andean lupin (Lupinus mutabilis) is a legume crop native to the South American Andes. Its seeds are high in protein but contain bitter quinolizidine alkaloids (QA), so they have traditionally been soaked in water to remove bitterness before eating. Total QA content is described as below 500 mg/kg in sweet varieties and above 10,000 mg/kg in bitter varieties; 1 report of 31,000 mg/kg for L. mutabilis has been identified. The assessment itself explicitly notes that this value comes from that 1 report only and is not corroborated by multiple studies.

The alkaloid composition of the seeds is not uniform either. A public assessment summarizes lupanine as accounting for 47–58% of the quinolizidine alkaloids in L. mutabilis, followed by sparteine at 7.4–16% and 13α-hydroxylupanine at 7–15%. The cultivars in the underlying data are not specified, so it is not known which cultivars this composition represents.

Sources for this overview

  1. Scientific opinion on the risks for animal and human health related to the presence of quinolizidine alkaloids in feed and food, in particular in lupins and lupin-derived products

    EFSA CONTAM Panel; Schrenk D; ほか / 2019 / government document / full text checked

    Checked for this overview: Checked the QA content categories for sweet and bitter varieties and the value of 31,000mg/kg. / Checked the composition figures in the main text, including 47-58% for lupanine.

  2. Lupinus mutabilis: Composition, Uses, Toxicology, and Debittering

    Carvajal-Larenas FE; Linnemann AR; Nout MJR; Koziol M; van Boekel MAJS / 2016 / review / full text checked

    Checked for this overview: Checked the statement that lupins contain bitter alkaloids.

Follow the connections

Andean lupin →contains→ quinolizidine alkaloids →— sensory attribute→ bitterness

lupanine →is the major quinolizidine …→ Andean lupin

Measured values (1)

KindCompoundTargetValueConditionsSource
concentrationquinolizidine alkaloidsAndean lupin31000 mg/kgLupinus mutabilis seeds (variety not stated). (EFSA explicitly states that there is only one report of total QA.)EFSA CONTAM Panel, 2019

Values are the reported values of each source (with units and conditions). Thresholds and EC50 depend on the panel and method; they are not single true values.

Hypotheses and recipe candidates for this entry are on the Japanese page.

Structured claims — open a section to read each claim's confidence, evidence and limits

Composition and content (3)

Andean lupin contains quinolizidine alkaloidssupported

Scope: Seeds

Note: The total QA figure of 31,000 mg/kg for L. mutabilis is a single report (EFSA states explicitly: "Only one paper reporting the total amount of QAs was identified").

States the distinction of sweet cultivars <500 mg/kg and bitter cultivars >10,000 mg/kg. Total QA for L. mutabilis is 31,000 mg/kg (only 1 paper reporting the total amount of QAs was reported to have been found).
Limitations: The total QA figure for L. mutabilis is a single report.
States that lupins contain alkaloids that taste bitter.
Limitations: Abstract level only.
Source: Lupinus mutabilis: Composition, Uses, Toxicology, and Debittering (Carvajal-Larenas FE; Linnemann AR; Nout MJR; Koziol M; van Boekel MAJS, 2016) · full text checked
Show dataorganism-lupinus-mutabilis —contains→ compound-class-quinolizidine-alkaloids
claim: clm-lupin-qa-content / type: composition / updated: 2026-08-31
lupanine is the major quinolizidine alkaloid of Andean lupinsupported

Scope: EFSA 2019's table of QA composition by species

The row for L. mutabilis lists a composition including lupanine 47-58%, sparteine 7.4-16%, and 13α-OH-lupanine 7-15%, among others.
Limitations: The cultivar in the source data is "Not stated."
Show datacompound-lupanine —is_the_major_quinolizidine_alkaloid_of→ organism-lupinus-mutabilis
claim: clm-lupanine-major-qa / type: composition / updated: 2026-08-31
Andean lupin — cultivar: 'Inti', bred through reselection of a low-alkaloid line. Alkaloid content under 0.02%. Recorded as bred through reselection in the early 1980s (Gross et al. 1988).supported

Scope: Lupinus mutabilis

Note: An example of debittering through breeding, in contrast to the existing process-lupin-debittering (traditional debittering by water treatment). However, whether 'Inti' has become widely commercially adopted cannot be confirmed from this material.

States that the low-alkaloid L. mutabilis cultivar 'Inti' (alkaloid content under 0.02%) was bred through reselection in the early 1980s and recorded in Gross et al. 1988.
Limitations: A secondhand citation via a review; the original Gross et al. 1988 paper was not read this time. The commercial adoption status of 'Inti' cannot be confirmed from this material.
Source: Quinolizidine Alkaloid Biosynthesis in Lupins and Prospects for Grain Quality Improvement (Frick KM; Kamphuis LG; Siddique KHM; Singh KB; Foley RC, 2017) · full text checked
Show dataorganism-lupinus-mutabilis —has_cultivar→ (the claim sentence above)
claim: clm-lupinus-mutabilis-inti-cultivar / type: composition / updated: 2026-09-02

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